Dendritic Cell-gp100-MART-1 Antigen Vaccine

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** An autologous dendritic cells vaccine with antineoplastic property. Dendritic cells harvested from cancer patients are pulsed with human gp100 melanoma antigen and MART-1 (melanoma antigen recognized by T-cells) antigen; both antigens are up-regulated in melanomas. Vaccination with this vaccine may elicit the host immune response against MART-1 or gp100 expressing cells.

**Synonyms:** - gp100/Mart-1-transduced dendritic cell vaccine