PCCA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PCCA wild-type allele is located in the vicinity of 13q32.3 and is approximately 441 kb in length. This allele, which encodes propionyl-CoA carboxylase alpha chain, mitochondrial protein, plays a role in regulating the carboxylation of butynyl- and propionyl-CoA and in the catabolism of various fatty acids and branched-chain amino acids. Mutations in the gene are associated with propionic acidemia type 1.

**Synonyms:** - PccA Complementation Group Gene - Propionyl CoA Carboxylase, Alpha Polypeptide Gene - Propionyl Coenzyme A Carboxylase, Alpha Polypeptide Gene - Propionyl-CoA Carboxylase Alpha Subunit Gene - Propionyl-CoA Carboxylase Subunit Alpha wt Allele - Propionyl-CoA Carboxylase, Alpha Subunit Gene