ANAPC1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ANAPC1 wild-type allele is located in the vicinity of 2q13 and is approximately 273 kb in length. This allele, which encodes anaphase-promoting complex subunit 1 protein, is involved in cell cycle regulation and protein polyubiquitination. Mutations in the gene are associated with Rothmund-Thomson syndrome type 1.

**Synonyms:** - APC1 - Anaphase Promoting Complex Subunit 1 wt Allele - Anaphase-Promoting Complex 1 (Meiotic Checkpoint Regulator) Gene - Anaphase-Promoting Complex, Subunit 1 Gene - MCPR - TSG24 - Testis-Specific Gene 24