Anaphase-Promoting Complex Subunit 1

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Anaphase-promoting complex subunit 1 (1944 aa, ~217 kDa) is encoded by the human ANAPC1 gene. This protein plays a role in the regulation of the E3 ubiquitin ligase activity of the anaphase promoting complex (cyclosome), which mediates cell cycle progression.

**Synonyms:** - ANAPC1 - APC1 - Cyclosome Subunit 1 - Mitotic Checkpoint Regulator - Testis-Specific Gene 24 Protein