PGC wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PGC wild-type allele is located in the vicinity of 6p21.1 and is approximately 17 kb in length. This allele, which encodes gastricsin protein, plays a role in aspartic-type endoproteolysis. Certain polymorphisms in the gene are associated with increased susceptibility to gastric cancers.

**Synonyms:** - PEPC - PGII - Pepcinogen C Gastricsin Gene - Pepsin C Gene - Pepsinogen C Gene - Pepsinogen Group II Gene - Pepsinogen, Group II Gene - Preprogastricsin Gene - Progastricsin (Pepsinogen C) Gene - Progastricsin wt Allele