PIGT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PIGT wild-type allele is located in the vicinity of 20q13.12 and is approximately 41 kb in length. This allele, which encodes GPI-anchor transamidase component PIGT protein, plays a role in regulation of the glycosylphosphatidylinositol (GPI) anchor transaminase complex. Mutations in the gene are associated with paroxysmal nocturnal hemoglobinuria 2 and multiple congenital anomalies-hypotonia-seizures syndrome 3.

**Synonyms:** - CGI-06 - GPI Transamidase Subunit Gene - MCAHS3 - NDAP - Neuronal Development-Associated Protein Gene - Neurotrophin-Regulated Neuronal Development-Associated Protein Gene - PIG-T - PNH2 - Phosphatidylinositol Glycan Anchor Biosynthesis Class T wt Allele - Phosphatidylinositol Glycan, Class T Gene