HCN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HCN1 wild-type allele is located in the vicinity of 5p12 and is approximately 442 kb in length. This allele, which encodes potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 protein, plays a role in the transport of potassium and sodium ions, which regulates multiple processes including the maintenance of pacemaker currents in the heart and neurons. Mutations in the gene are associated with developmental and epileptic encephalopathy 24 and generalized epilepsy with febrile seizures plus, type 10.

**Synonyms:** - BCNG-1 - BCNG1 - Brain Cyclic-Nucleotide Gated 1 Gene - DEE24 - EIEE24 - GEFSP10 - HAC-2 - Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 1 wt Allele - Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 Gene - Potassium-Channel, Voltage-Gated, Brain, 1 Gene