Stage II Nasopharyngeal Carcinoma AJCC v9

**Semantic type:** Neoplastic Process

**Definition:** Stage II includes: (T0-T2, N2, M0); (T3, N0-N2, M0). T0: No evidence of primary tumor identified, but EBV-positive cervical node(s) involvement is present. T1: Tumor confined to nasopharynx or tumor extension to any of the following without parapharyngeal involvement: oropharynx, nasal cavity. T2: Tumor extension to any of the following: parapharyngeal space, adjacent soft tissue involvement of medial pterygoid, lateral pterygoid, prevertebral muscles. T3: Tumor unequivocal infiltration into any of the following bony structures: skull base (including pterygoid structures), paranasal sinuses, cervical vertebrae. N0: No tumor involvement of regional lymph node(s). N1: Tumor involvement of any of the following: unilateral cervical lymph node(s), unilateral or bilateral metastasis in retropharyngeal lymph node(s), and all of the following: 6 cm or less in greatest dimension, above the caudal border of cricoid cartilage, without advanced extranodal extension. N2: Tumor involvement of bilateral cervical lymph nodes and all of the following: 6 cm or less in greatest dimension, above the caudal border of cricoid cartilage, without advanced extranodal extension. M0: No distant metastasis. (AJCC 9th ed.)