Apolizumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro. (NCI04)

**Synonyms:** - 1D10 Anti-lymphoma Antibody - APOLIZUMAB - MAbHu1D10 - MoAb Hu1D10 - MoAb: Hu1D10 - Monoclonal Antibody Hu1D10 - Monoclonal antibody 1D10 - Remitogen - apolizumab