Alkylating Agent

**Semantic type:** Chemical Viewed Functionally

**Definition:** Agents that replace hydrogen atom(s) in biologically active molecules with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cell growth.

**Synonyms:** - Alkylating Agents - Alkylator - alkylating agent