KRT4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KRT4 wild-type allele is located in the vicinity of 12q13.13 and is approximately 8 kb in length. This allele, which encodes keratin, type II cytoskeletal 4 protein, plays a role in the structure of mucosal and esophageal epithelia. Mutations in the gene are associated with white sponge nevus 1.

**Synonyms:** - CK-4 - CK4 - CYK4 - Cytokeratin 4 Gene - K4 - KB4 - Keratin 4 wt Allele - Keratin 4, Type II Gene - Keratin, Type II Cytoskeletal 4 Gene - WSN1