LAMB3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LAMB3 wild-type allele is located in the vicinity of 1q32.2 and is approximately 38 kb in length. This allele, which encodes laminin subunit beta-3 protein, is involved in endodermal cell differentiation and the development of the epidermis. Mutations in the gene are associated with amelogenesis imperfecta IA and junctional epidermolysis bullosa types 1A (intermediate) and 1B (severe).

**Synonyms:** - AI1A - BM600-125kDa Gene - JEB1A - JEB1B - Kalinin-140kDa Gene - LAM5 - LAM5, Beta-3 Subunit Gene - LAMNB1 - Laminin 5 B3 Chain Gene - Laminin 5, Beta-3 Subunit Gene - Laminin B3 Gene - Laminin Beta 3 Gene - Laminin Subunit Beta 3 wt Allele - Laminin, Beta 3 (Nicein (125kD), Kalinin (140kD), BM600 (125kD)) Gene - Laminin, Beta 3 Gene - Laminin, Beta-3 Gene - Nicein-125kDa Gene