TSEN15 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TSEN15 wild-type allele is located in the vicinity of 1q25.3 and is approximately 72 kb in length. This allele, which encodes tRNA-splicing endonuclease subunit Sen15 protein, plays a role in the removal of introns from pre-tRNAs. Mutations in the gene are associated with pontocerebellar hypoplasia type 2F.

**Synonyms:** - C1orf19 - Chromosome 1 Open Reading Frame 19 Gene - PCH2F - SEN15 - SEN15, Yeast, Homolog of Gene - TSEN15 tRNA Splicing Endonuclease Subunit Gene - sen15 - tRNA Splicing Endonuclease 15 Homolog (S. cerevisiae) Gene - tRNA Splicing Endonuclease 15 Homolog Gene - tRNA Splicing Endonuclease 15, S. cerevisiae, Homolog of Gene - tRNA Splicing Endonuclease Subunit 15 wt Allele - tRNA Splicing Endonuclease, Subunit 15 Gene