TSEN2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TSEN2 wild-type allele is located in the vicinity of 3p25.2 and is approximately 61 kb in length. This allele, which encodes tRNA-splicing endonuclease subunit Sen2 protein, is involved in tRNA intron splice site recognition and cleavage and in mRNA processing. Mutations in the gene are associated with pontocerebellar hypoplasia type 2B.

**Synonyms:** - MGC2776 - PCH2B - SEN2 - SEN2, Yeast, Homolog of Gene - SEN2L - TSEN2 tRNA Splicing Endonuclease Subunit Gene - sen2 - tRNA Splicing Endonuclease 2 Homolog (S. cerevisiae) Gene - tRNA Splicing Endonuclease 2 Homolog Gene - tRNA Splicing Endonuclease 2, S. cerevisiae, Homolog of Gene - tRNA Splicing Endonuclease Subunit 2 wt Allele - tRNA Splicing Endonuclease, Subunit 2 Gene