Yttrium Y 86-NM600

**Semantic type:** Indicator, Reagent, or Diagnostic Aid|Pharmacologic Substance

**Definition:** A radioconjugate composed of NM600, a tumor-selective alkylphosphocholine (APCh) analog, conjugated with the radioisotope yttrium 86 (Y-86), with potential imaging activity upon positron emission tomography (PET). Upon administration of yttrium Y 86-NM600, NM600 is selectively taken up by tumor cells via membrane lipid rafts and accumulates in tumor cells. Upon PET imaging, tumor cells can be visualized. Cancer cells have higher level of lipid rafts, which play an important role in cancer cell metastasis and cell death.

**Synonyms:** - 86Y-NM600 - Yttrium Y 86 NM600