CACNB2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CACNB2 wild-type allele is located in the vicinity of 10p12 and is approximately 403 kb in length. This allele, which encodes voltage-dependent L-type calcium channel subunit beta-2 protein, is involved in heart rate, muscle contraction and calcium transport. Mutations in the gene are associated with Brugada syndrome 4.

**Synonyms:** - CAB2 - CACNLB2 - CAVB2 - Ca(V) Beta-2 Gene - Calcium Channel, Voltage-Dependent, Beta 2 Subunit Gene; - Calcium Channel, Voltage-Dependent, Beta-2 Subunit Gene - Calcium Voltage-Gated Channel Auxiliary Subunit Beta 2 wt Allele - Lambert-Eaton Myasthenic Syndrome Antigen Gene - MYSB - Myasthenic (Lambert-Eaton) Syndrome Antigen B Gene - Myasthenic Syndrome Antigen B Gene