KCNE3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KCNE3 wild-type allele is located in the vicinity of 11q13.4 and is approximately 13 kb in length. This allele, which encodes potassium voltage-gated channel subfamily E member 3 protein, plays a role in modulation of the gating kinetics and stability of voltage-gated potassium channel complexes. Mutations in the gene are associated with Brugada syndrome 6 and may be associated with hypokalemic periodic paralysis.

**Synonyms:** - BRGDA6 - Cardiac Voltage-Gated Potassium Channel Accessory Subunit Gene - HOKPP - HYPP - MiRP2 - Potassium Channel, Voltage Gated Subfamily E Regulatory Beta Subunit 3 Gene - Potassium Voltage-Gated Channel Subfamily E Regulatory Subunit 3 wt Allele - Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 Gene - Potassium-Channel, Voltage-Gated, Isk-Related Subfamily, Member 3 Gene - Voltage-Gated K+ Channel Subunit MIRP2 Gene