PROP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PROP1 wild-type allele is located in the vicinity of 5q35.3 and is approximately 4 kb in length. This allele, which encodes homeobox protein prophet of Pit-1 protein, plays a role in pituitary development and function. Mutations in the gene are associated with combined pituitary hormone deficiency 2.

**Synonyms:** - CPHD2 - PROP Paired-Like Homeobox 1 wt Allele - PROP-1 - Prophet of Pit1, Paired-Like Homeodomain Transcription Factor Gene