GPX4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GPX4 wild-type allele is located in the vicinity of 19p13.3 and is approximately 3 kb in length. This allele, which encodes phospholipid hydroperoxide glutathione peroxidase GPX4 protein, plays a role in antioxidant peroxidase activity. Mutations in the gene are associated with Sedaghatian spondylometaphyseal dysplasia.

**Synonyms:** - GPx-4 - GSHPx-4 - Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase) Gene - Glutathione Peroxidase 4 wt Allele - MCSP - PHGPx - Phospholipid Hydroperoxidase Gene - Phospholipid Hydroperoxide Glutathione Peroxidase Gene - Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial Gene - SMDS - Selenoprotein GPX4 Gene - Sperm Nucleus Glutathione Peroxidase Gene - snGPx - snPHGPx