Tariquidar

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An anthranilamide derivative with multidrug resistance properties. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. (NCI04)

**Synonyms:** - TARIQUIDAR - XR9576 - XR9576 - tariquidar