Acetyl-CoA Carboxylase 2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Acetyl-CoA carboxylase 2 (2458 aa, ~277 kDa) is encoded by the human ACACB gene. This protein plays a role in binding to and ATP-dependent carboxylation of biotin, followed by transfer of the carboxyl group from biotin to acetyl-CoA that yields malonyl-CoA.

**Synonyms:** - ACACB - ACC-Beta - Acetyl-CoA Carboxylase Beta - Acetyl-Coenzyme A Carboxylase 2 - Acetyl-Coenzyme A Carboxylase Beta - EC 6.4.1.2