FLNB wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FLNB wild-type allele is located in the vicinity of 3p14.3 and is approximately 164 kb in length. This allele, which encodes filamin-B protein, is involved in the regulation of cell proliferation, differentiation, and migration. Mutations in the gene are associated with boomerang dysplasia, autosomal dominant Larsen syndrome, spondylocarpotarsal synostosis syndrome and atelosteogenesis types 1 and 3.

**Synonyms:** - ABP-278 - ABP-280 - AOI - ASC1 - Actin Binding Protein 278 Gene - Actin-Binding Protein, Truncated Gene - Beta Filamin Gene - FH1 - FLN-B - FLN1L - FLN3 - Filamin B wt Allele - Filamin B, Beta (Actin Binding Protein 278) Gene - Filamin B, Beta Gene - Filamin, Beta Gene - LRS1 - Larsen Syndrome 1 (Autosomal Dominant) Gene - SCT - TABP - TAP