C224848Level 6
Antibody-drug Conjugate ABBV-324
**Semantic type:** Pharmacologic Substance
**Definition:** An antibody-drug conjugate (ADC) composed of an as of yet undisclosed monoclonal antibody directed against a tumor-associated antigen (TAA) linked to an as of yet undisclosed cytotoxic agent, with potential antineoplastic activity. Upon administration, the monoclonal antibody moiety of ADC ABBV-324 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an as of yet unknown mechanism of action.
**Synonyms:** - ABBV 324 - ABBV-324 - ABBV324 - ADC ABBV-324
GET
/api/v1/systems/nci_thesaurus/nodes/C224848Hierarchy Explorer
Loading...
Cross-system equivalences0
No cross-system equivalences mapped for this node.