Antibody-drug Conjugate SLV-154

**Semantic type:** Pharmacologic Substance

**Definition:** An antibody-drug conjugate (ADC) composed of an as of yet undisclosed monoclonal antibody directed against a tumor-associated antigen (TAA) linked, via cleavable, hydrophilic cleavable linker, to an as of yet undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of ADC SLV-154 targets and binds to the TAA expressed on tumor cells. Upon binding, internalization, and linker cleavage, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an as of yet unknown mechanism of action.

**Synonyms:** - ADC SLV-154 - SLV 154 - SLV-154 - SLV154