Dezandrodeg

**Semantic type:** Pharmacologic Substance

**Definition:** An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity. Upon administration, dezandrodeg causes degradation of AR, prevents AR-mediated signaling and inhibits the proliferation of AR-overexpressing tumor cells. AR plays a key role in tumor cell proliferation in castration-resistant prostate cancer (CRPC).

**Synonyms:** - AR Degrader CC-94676 - Androgen Receptor Degrader CC-94676 - BMS 986365 - BMS-986365 - BMS986365 - CC 94676 - CC-94676 - CC94676 - CEL 007452 - CEL-007452 - CEL007452 - DEZANDRODEG