Bispecific T-cell Engager NRM-823

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A bispecific T-cell engager (TCE) directed against an as of yet undisclosed tumor-associated antigen (TAA) expressed on certain tumor cells and an as of yet undisclosed T-cell surface antigen, with potential immunostimulating and antineoplastic activities. Upon administration, bispecific TCE NRM-823 specifically targets and binds to both the TAA on tumor cells and the antigen on T-cells. This results in the cross-linking of tumor cells and T-cells, and induces a cytotoxic T-lymphocyte (CTL) response against the TAA-expressing tumor cells.

**Synonyms:** - Bispecific TCE NRM-823 - NRM 823 - NRM-823 - NRM823 - TCE NRM-823