t(11;16)(q23;p13.3)

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A chromosomal translocation involving breakpoints within the q23 band on the long arm of chromosome 11 and the p13.3 band on the short arm of chromosome 16. It is associated with KMT2A-CREBBP fusion gene expression and with myelodysplastic syndrome (MDS) and MDS-associated acute leukemia.