Testolactone

**Semantic type:** Hormone|Organic Chemical|Pharmacologic Substance

**Definition:** A progesterone derivative with antineoplastic activity. Testolactone inhibits steroid aromatase, thereby preventing the formation of estrogen from adrenal androstenedione and reducing endogenous estrogen levels. (NCI04)

**Synonyms:** - 1,2,3,4,4a,4b,7,9,10,10a-Decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic Acid Delta-Lactone - 1-Dehydrotestololactone - 13-Hydroxy-3-0x0-13,17-secoandrosta-1,4-dien-17-oic Acid Delta-Lactone - 17Alpha-oxo-D-homo-1,4-androstadiene-3,17-dione - D-Homo-17a-oxaandrosta-1,4-diene-3,17-dione - Delta-1-Testololactone - Fludestrin - Fludestrin - SQ 9538 - SQ-9538 - TESTOLACTONE - Teslac - Teslac - Therapeutic Testolactone