I 131 Antiferritin Immunoglobulin

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A radioimmunoconjugate of a rabbit antihuman ferritin IgG labeled with iodine 131 (I-131). Using anti-ferritin IgG as a carrier for I-131 may result in the targeted imaging and/or destruction of cells expressing ferritin. Observed in 35% to 100% of patients with hepatocellular carcinoma, high serum ferritin levels may be due to ferritin production by the tumor cells, or related to the associated iron overload and/or cirrhosis.

**Synonyms:** - I 131-AFI - I 131-antiferritin IgG - Iodine I 131 Antiferritin Immunoglobulin - immunoglobulin, iodine I 131 antiferritin