Monoclonal Antibody 14G2A

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and induces antibody-dependent cell mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI04)

**Synonyms:** - 14G2A - 14G2A, monoclonal antibody - Antibody 14G2A, Monoclonal - MURINE MONOCLONAL ANTI-GD2 ANTIBODY 14G2A - MoAb 14G2A