Monoclonal Antibody LL2

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A murine monoclonal antibody (MoAb) IgG2a, LL2. MoAb LL2 recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in progenitor B cells, and as a cell surface protein in mature B cells. When labeled with radioisotope, MoAb LL2 targets tumor cells that express CD22 antigen and delivers cytotoxic radiation that may be used to treat B-cell lineage cancers.

**Synonyms:** - Anti-CD22 Monoclonal Antibody, LL2 - LL2 - LL2 monoclonal antibody - MoAb LL2