Rasburicase

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A recombinant urate oxidase enzyme isolated from a genetically-modified strain of Saccharomyces cerevisiae. Urate oxidase catalyzes the oxidation of uric acid to the excretable metabolite allantoin, a molecule that is 5-10 times more water-soluble than uric acid. An enzyme that occurs endogenously in most mammals, urate oxidase is not found in humans. (NCI04)

**Synonyms:** - Elitek - Elitek - RASBURICASE - Recombinant Urate Oxidase - SR 29142 - SR-29142 - SR-29142 - Urate Oxidase - rasburicase - recombinant urate oxidase