Iodine I 131 Monoclonal Antibody 3F8

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic properties. Using monoclonal antibody 3F8 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing GD2. GD2 is a ganglioside which is overexpressed in malignant melanoma, neuroblastoma, and small cell carcinoma of the lung. (NCI04)

**Synonyms:** - (131I)-3F8 - ANTI-GD2 MONOCLONAL ANTIBODY 3F8 I-131 - I 131 Monoclonal Antibody 3F8 - iodine I 131 MOAB 3F8