Iodine I 131 Tositumomab

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A monoclonal antibody directed against the CD20 protein expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope iodine I 131 with potential antineoplastic activity. Iodine I 131 tositumomab binds to and selectively delivers cyctotoxic radiation to CD20-expressing B-lymphocytes, thereby minimizing systemic radiotoxicity.

**Synonyms:** - 131-I-Anti-B1 Monoclonal Antibody - Bexxar - I 131 Monoclonal Antibody Anti-B1 - I 131 Tositumomab - I131-MOAB-B1 - Iodine I 131 MOAB Anti-B1 - Iodine I 131 Monoclonal Antibody Anti-B1 - Iodine-131 Anti-B1 Antibody - Iodine-131 Anti-CD20 Monoclonal Antibody - Iodine-131 Tositumomab - TOSITUMOMAB I-131 - Tositumomab and I-131 - iodine I 131 tositumomab