Palifermin

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A recombinant form of the endogenous human keratinocyte growth factor with cell growth promoting activity. Palifermin acts in the manner similar to the endogenous keratinocyte growth factor that binds to keratinocyte growth factor receptors on the epithelial cell surface in the lining of mouth and gastrointestinal tract. This results in stimulation of epithelial cell proliferation, differentiation and upregulation of cytoprotective mechanisms.

**Synonyms:** - Growth Factor, Recombinant Human Keratinocyte - Kepivance - Kepivance - Keratinocyte Growth Factor, Recombinant Human - PALIFERMIN - Recombinant Human Keratinocyte Growth Factor - palifermin - rhKGF - rhu Keratinocyte Growth Factor