Iodine I 131 Monoclonal Antibody 81C6

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using monoclonal antibody 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. Tenascin is an extracellular matrix protein which is overexpressed in gliomas and other cancers.

**Synonyms:** - 81C6-I-131 - I 131 Monoclonal Antibody 81C6 - IODINE I-131 MONOCLONAL ANTIBODY 81C6 - Neuradiab - iodine I 131 MOAB 81C6