2IT-BAD Monoclonal Antibody 170

**Semantic type:** Amino Acid, Peptide, or Protein|Indicator, Reagent, or Diagnostic Aid|Pharmacologic Substance

**Definition:** An immunoconjugate of a metal chelator, 2IT-BAD (2-iminothiolane-2-[p-(bromoacetamido)benzyl]-1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid), and a panadenocarcinoma murine monoclonal antibody (MoAb) m170. MoAb m170 recognizes MUC-1 antigen present on the surface of many adenocarcinomas. 2IT-BAD MoAb m170 can readily chelate any radioisotope and be used in diagnostic procedures or in the treatment of MUC-1 expressing adenocarcinomas.

**Synonyms:** - 2IT-BAD monoclonal antibody 170