C2543Level 6
Tositumomab
**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance
**Definition:** A murine IgG2 monoclonal antibody directed against the CD20 antigen, found on the surface of B-cells. Tositumomab binds to the CD20 surface membrane antigen, resulting in apoptosis, and may stimulate antitumoral cell-mediated and/or antibody-dependent cytotoxicity. (NCI04)
**Synonyms:** - Anti-CD20 Antibody - MoAb Anti-B1 - Monoclonal Antibody Anti-B1 - TOSITUMOMAB - anti-B1 - tositumomab
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