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C2548Level 5

Prostatic Acid Phosphatase-Sargramostim Fusion Protein PA2024

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A genetically-engineered protein formed by the fusion of prostatic acid phosphatase (PAP) and sargramostim (GM-CSF). Vaccination with antigen-presenting cells (APC) loaded with prostatic acid phosphatase-sargramostim fusion protein may elicit a cytotoxic T-cell response against tumor cells that express PAP. (NCI05)

**Synonyms:** - PA2024 - PROSTATIC ACID PHOSPHATASE (PAP)-GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) FUSION PROTEIN

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