Chemokine Receptor Gene

**Semantic type:** Gene or Genome

**Definition:** Chemokine Receptor Genes (GPCR Family) encode cell surface Chemokine Receptors, seven-transmembrane G protein-coupled receptor glycoproteins that bind to chemokines and mediate the migration of pro-inflammatory cells. Like chemokines, the chemokine receptors can be divided, according to variations in a shared cysteine motif, into at least three structural branches: CR, CCR, and CXCR. (NCI)