ESO-1 Peptide Vaccine

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A cancer vaccine consisting of an immunogenic peptide sequence from the cancer-testis antigen ESO-1, an antigen found in normal testis and various tumors, including melanoma, breast, bladder, prostate, and hepatocellular cancers. Vaccination with ESO-1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte response against tumor cells that express ESO-1. (NCI04)