Frizzled Domain

**Semantic type:** Amino Acid Sequence

**Definition:** A 120 amino acid protein domain, with an alpha-helical structure, containing 10 cysteines, which have conserved spacing throughout the sequence. This domain is involved in the recognition of extracellular ligands.

**Synonyms:** - Frizzled CRD - Frizzled Cysteine-Rich Domain - Fz Domain