Telomerase: 540-548 Peptide Vaccine

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT). Telomerase expression has been directly linked to tumor development; its catalytic subunit is expressed in the majority of human cancer cells, but infrequently in normal cells. Vaccination with telomerase:540-548 peptide may stimulate cytotoxic T cells to recognize and kill telomerase-expressing cells. (NCI04)

**Synonyms:** - Telomerase:540-548 Peptide