Iratumumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Indicator, Reagent, or Diagnostic Aid|Pharmacologic Substance

**Definition:** A fully human monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized antibody that targets CD30, a member of the tumor necrosis factor receptor superfamily found on activated lymphocytes. CD30 is over-expressed in various lymphoproliferative disorders, Hodgkin disease and other lymphomas, and other cancers. (NCI04)

**Synonyms:** - IRATUMUMAB - MDX-060 - MDX-060 - Monoclonal Antibody MDX-060