Golnerminogene Pradenovec

**Semantic type:** Pharmacologic Substance

**Definition:** A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF.

**Synonyms:** - ADgv EGR.TNF.11D - Ad 5-TNF Alpha - Adenovirus 5-Tumor Necrosis Factor Alpha - TNFerade - TNFerade