Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Mitogen-activated protein kinase kinase kinase kinase 4 (1239 aa, ~142 kDa) is encoded by the human MAP4K4 gene. This protein is involved in serine/threonine phosphorylation and modulation of JNK signal pathways.

**Synonyms:** - EC 2.7.11.1 - HGK Protein - HPK/GCK-Like Kinase - HPK/GCK-Like Kinase HGK - Hematopoietic Progenitor Kinase/Germinal Center Kinase-Like Kinase - MAP4K4 - MAPK/ERK Kinase Kinase Kinase 4 - MEK Kinase Kinase 4 - MEKKK4 - NCK Interacting Kinase - Nck-Interacting Kinase