Pro-Platelet Basic Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A product of the PPBP gene, pro-platelet basic protein is processed into platelet basic protein (PBP) and connective-tissue-activating peptide III (CTAP-III). Upon platelet activation these proteins undergo further processing into beta thromboglobulin (Beta-TG) and neutrophil-activating peptide 2 (NAP2), respectively. Many of the function ascribed to CTAP-III may actually be the result of processing to NAP-2.

**Synonyms:** - CXC Chemokine Ligand 7 - PPBP - Platelet Basic Protein - Thrombocidin 1 - Thrombocidin 2