Modafinil

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04)

**Synonyms:** - MODAFINIL - Provigil - modafinil