Common Variable Immunodeficiency

**Semantic type:** Disease or Syndrome

**Definition:** A primary immunodeficiency characterized by low levels or absence of all the immunoglobulin classes and lack of B-lymphocytes or plasma cells. It results in recurrent bacterial infections. Complications include autoimmune phenomena and cancer development.

**Synonyms:** - Acquired Agammaglobulinemia - Acquired Hypogammaglobulinemia - Common variable immune deficiency (CVID) - Secondary Hypogammaglobulinemia - Secondary Hypogammaglobulinemia