Vaccinia-GM-CSF Vaccine

**Semantic type:** Chemical Viewed Functionally

**Definition:** A recombinant vaccinia virus that encodes granulocyte-macrophage colony stimulating factor (GM-CSF). By activating T-cells and macrophages, vaccination with recombinant vaccinia GM-CSF may enhance the host immune system response to poorly immunogenic tumors, resulting in decreased tumor growth. (NCI04)

**Synonyms:** - Recombinant Vaccinia-GM-CSF - rV GM-CSF